Semaglutide

$30.00 – $190.00

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Semaglutide used for the treatment of type 2 diabetes and obesity. Semaglutide mimics the action of glucagon-like peptide-1 (GLP-1)

SKU: A2LC33 Categories: Blood Sugar Control, Weight Management

Additional Information

As a glucagon-like peptide-1 receptor agonist (GLP-1 RA), it increases the secretion of the hormone insulin which helps the cells to effectively utilize energy. This process ensures proper fat storage and decreases blood glucose (blood sugar) levels. Semaglutide also suppresses your appetite and slows gastric emptying by blocking certain chemicals in the brain. This in turn helps promote fat loss. Semaglutide is important for long-term weight management due to its efficacy in promoting significant and sustained weight loss in adults with obesity. As a glucagon-like peptide-1 (GLP-1) receptor agonist, semaglutide works by mimicking the effects of the GLP-1 hormone, which regulates appetite and food intake. [1] The once-weekly injectable formulation of semaglutide has shown remarkable results in clinical trials, demonstrating greater weight loss compared to placebo and other weight-loss medications. By enhancing feelings of fullness, reducing hunger, and slowing down gastric emptying, semaglutide helps individuals achieve meaningful and durable weight reduction, making it a promising and valuable option for managing chronic weight issues and improving overall health outcomes.

Protocol

Compounded semaglutide is a form of semaglutide that is made by a compounding pharmacy. Compounding pharmacies are licensed to create customized medications for individual patients. In the case of compounded semaglutide, the pharmacy may combine semaglutide with other ingredients, such as vitamins or minerals, to create a medication that is tailored to the specific needs of the patient. Compounded semaglutide is often used as a weight loss medication. Semaglutide is a GLP-1 receptor agonist, which means that it works by binding to the GLP-1 receptor in the gut to help control blood sugar levels. However, semaglutide has also been shown to be effective at promoting weight loss. There are a few reasons why people might choose to use compounded semaglutide for weight loss. First, compounded semaglutide is often less expensive than brand-name semaglutide. Second, compounded semaglutide can be tailored to the specific needs of the patient. For example, if a patient has trouble swallowing pills, the compounding pharmacy can create a compounded semaglutide that is administered as a liquid or a nasal spray. However, there are also some risks associated with using compounded semaglutide. First, compounded semaglutide has not been as extensively studied as brand-name semaglutide. This means that there is less information available about the safety and efficacy of compounded semaglutide. Second, there is a risk that compounded semaglutide may not be made correctly. This could lead to the wrong dosage being given, or it could lead to the medication being contaminated. If you are considering using compounded semaglutide, talk to your doctor about the risks and benefits. Your doctor can help you decide if compounded semaglutide is right for you.

Clinical Research

Drucker D. J. (2018). Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1. Cell metabolism, 27(4), 740–756. https://doi.org/10.1016/j.cmet.2018.03.001 Wilding, J., Batterham, R. L., Calanna, S., Davies, M., Van Gaal, L. F., Lingvay, I., McGowan, B. M., Rosenstock, J., Tran, M., Wadden, T. A., Wharton, S., Yokote, K., Zeuthen, N., Kushner, R. F., & STEP 1 Study Group (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. The New England journal of medicine, 384(11), 989. https://doi.org/10.1056/NEJMoa2032183 Kushner, R. F., Calanna, S., Davies, M., Dicker, D., Garvey, W. T., Goldman, B., Lingvay, I., Thomsen, M., Wadden, T. A., Wharton, S., Wilding, J., &Rubino, D. (2020). Semaglutide 2.4 mg for the Treatment of Obesity: Key Elements of the STEP Trials 1 to 5. Obesity (Silver Spring, Md.), 28(6), 1050–1061. https://doi.org/10.1002/oby.22794 Christou, G. A., Katsiki, N., Blundell, J., Fruhbeck, G., &Kiortsis, D. N. (2019). Semaglutide as a promising antiobesity drug. Obesity reviews : an official journal of the International Association for the Study of Obesity, 20(6), 805–815. https://doi.org/10.1111/obr.12839 Rubino, D., Abrahamsson, N., Davies, M., Hesse, D., Greenway, F. L., Jensen, C., Lingvay, I., Mosenzon, O., Rosenstock, J., Rubio, M. A., Rudofsky, G., Tadayon, S., Wadden, T. A., Dicker, D., & STEP 4 Investigators (2021). Effect of Continued Weekly Subcutaneous Semaglutidevs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial. JAMA, 325(14), 1414–1425. https://doi.org/10.1001/jama.2021.3224

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Semaglutide

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