Semax

Lowers the Risk of Heart Disease

A number of convincing studies show that Semax can help protect against heart disease:

1. In mice, Semax produced beneficial effects on cardiac remodeling and decreased the risk of heart failure after a heart attack. [1]
2. In mice, administration of Semax prevented the alteration of the heart’s function caused by the restriction of blood supply. [2]
3. A study showed that Semax improved the functions of the cardiovascular system. [3]
4. In rats with experimental myocardial infarction, Semax increased heart rate and reduced stress on the different heart structures. [4]
5. A rat study reported that Semax can help increase heart rate by affecting the electrical conduction system of the heart. [5]

Boosts Immunity

Evidence suggests that Semaxcan help strengthen the immune system:

1. A study reported that Semax’s immune-modulating properties were effective in treating stress-induced immune imbalance. [6]
2. A study also found that Semax can help boost immunity by regulating the activities of immune system cells. [7]

Accelerates Wound Healing

Semax has also been found to possess regenerative properties:

1. A study reported that Semax shortened the healing time of acetic ulcers by reducing inflammation in the ulcer zone. [8]
2. In rats, Semaxinjections inhibited the formation of acetic acid ulcers. [9]

Improves Brain Health and Performance

An overwhelming body of evidence supports the beneficial effects of Semax on brain function:

1. In animal models, intranasal administration of Semaximproved learning and memory. [10]
2. In rats, Semax administration improved cognitive function by stimulating the production of brain-derived neurotrophic factor (BDNF). [11]
3. In mice, Semaxshowed cognitive-enhancing effects with increased BDNF levels. [12]
4. A study suggested that Semax can help treat memory disorders associated with decreased blood supply to the brain. [13]
5. A study showed that Semax can help protect against metal-induced brain toxicity. [14]
6. In rats, intranasal administration of Semax was effective in rapid and specific activation of BDNF and growth factor gene (NGF) in different brain regions. [15]
7. In rats with Parkinson’s disease, Semax improved performance in a test assessing memory. [16]
8. A study found that Semax can help improve learning ability by stabilizing the levels of the anti-stress peptides known as enkephalins. [17]
9. In healthy volunteers, Semax increased the function of the default mode network of the brain. [18]
10. In epileptic mice, Semax provided protective effects against learning and memory deficits. [19]

Lowers the Risk of Stroke

Aside from boosting brain function, Semax also has protective effects against stroke:

1. In patients with cerebrovascular insufficiency, a condition characterized by obstruction in the brain arteries resulting in reduced blood supply, Semax treatment inhibited disease progression and reduced the risk of stroke attacks. [20]
2. A study showed that high doses of Semax (100-150 micrograms/kg) prevented acute ischemic stroke. [21]
3. In rats, Semax protected against injury caused by sudden blood flow to the brain. [22]
4. In patients with stroke, Semax treatment had beneficial effects on the rate of restoration of the damaged neurological functions. [23]
5. In patients who were at different stages of stroke, Semax administration accelerated functional recovery and improved motor performance. [24]
6. A rat study found that Semax prevented stroke by reducing the occlusion of brain arteries. [25]

Improves Mood

Studies also show that Semax has antidepressant and anti-anxiety effects:

1. In white rats, Semax significantly diminished neonatal stress. [26]
2. A study reported that Semax can be a therapeutic option for depression. [27]
3. In rats, Semax administration improved performance in a test assessing anxiety. [28]
4. A rat study also found that Semax injections induced antidepressant and anti-anxiety effects after 1-14 days. [29]
5. In rodents, Semax injections improved mood by increasing the levels of the brain chemical known as dopamine. [30]